What is β–Amyloid (1-42),human Amyloid β-Protein (Human, 1-42)

Products Name: β–Amyloid (1-42),human Amyloid β-Protein (Human, 1-42)
Molecular Formula: C203H311N55O60S
Purity (HPLC):  98%min.
Appearance: White powder

β–Amyloid (1-42),human Amyloid β-Protein (Human, 1-42) is the main component of amyloid plaques (deposits found in the brains of patients with Alzheimer's disease). Similar plaques appear in some variants of Lewy body dementia and in inclusion body myositis (a muscle disease), while β–Amyloid (1-42),human Amyloid β-Protein (Human, 1-42) can also form the aggregates that coat cerebral blood vessels in cerebral amyloid angiopathy. The plaques are composed of a tangle of regularly ordered fibrillar aggregates called amyloid fibers, a protein fold shared by other peptides such as the prions associated with protein misfolding diseases. Recent research suggests that soluble oligomeric forms of the peptide may be causative agents in the development of Alzheimer's disease A number of genetic, cell biology, biochemical and animal studies support the concept that Aβ plays a central role in the development of Alzheimer’s disease pathology.

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